The areas of medicinal chemistry and pharmacognosy focus on the interdisciplinary application of chemical and biochemical principles to the identification and development of therapeutic agents. Research in medicinal chemistry includes the synthesis of organic medicinal products, elucidation of the biochemistry of medicinal agents, examination of the relationship of chemical structure to biological activity, qualitative and quantitative analysis of drugs and related products, and application of computational chemistry to drug design. Research in pharmacognosy encompasses the isolation and structure determination of pharmacologically active natural products from plants and microbes, studies on the structure and biochemistry of biological products, examination of the biosynthesis of natural products, and evaluation of the biochemical effects of these active constituents.
The Division of Medicinal Chemistry and Pharmacognosy is composed of faculty members with diversified research interests representing synthetic organic, analytical, natural products, and biological chemistry as well as computerized data acquisition control systems. Our graduate program and research interests are strongly tied to interdisciplinary approaches to the solution of chemical and biochemical problems. Our faculty are also active participants in The Ohio State University Comprehensive Cancer Center and are responsible for the operation and research of the Radiochemistry and Instrumentation Laboratory of the Cancer Center. Some of our faculty also participate in the Ohio State Biochemistry Program on campus. The research within the Division involves interaction with all other units of the College of Pharmacy as well as studies involving the Colleges of Biological Sciences, Medicine, Veterinary Medicine, and Dentistry.
In the Division of Medicinal Chemistry and Pharmacognosy, your program will involve course work in the Division of Medicinal Chemistry and Pharmacognosy as well as the Departments of Chemistry and Biochemistry. A research project is also undertaken for the preparation of a dissertation required to earn a graduate degree. Your course work consists of advanced organic chemistry, biochemistry, and medicinal chemistry and pharmacognosy, and includes instrumental analysis and chemical isolation methods.
We currently have available research and teaching assistantships, and University fellowships to support your graduate studies. Several of our students are supported by fellowships from the American Foundation for Pharmaceutical Education and the National Institutes of Health. Students supported on a stipend receive a waiver of tuition that considerably increases the value of the stipend. Our program currently includes 30 graduate students and 10 postdoctoral research associates.
Each year we participate in student medicinal chemistry meetings during which graduate students present their research. Hosting of the meetings rotates between The Ohio State University, The University of Michigan, Purdue University, and the State University of New York at Buffalo. These meetings are organized by the students and supported by the pharmaceutical industry.