BMRB’s mission is to collect, archive, and disseminate (worldwide in the public domain) the important quantitative data derived from NMR spectroscopic investigations of biological macromolecules. Relevant data are deposited by the scientists who generate them, and in consultation with these scientists, BMRB resolves any problems with the self-consistency and completeness of the deposition. In collaboration with the Protein Data Bank, BMRB provides links between the spectral data and associated atomic coordinates. BMRB works with the user community to develop formats for these data that can be parsed by computers and used for knowledge generation, alone and in conjunction with information from other databases. BMRB’s goal is to empower scientists in their analysis of the structure, dynamics, and chemistry of biological systems and to support further development of the field of biomolecular NMR spectroscopy. Through international collaborations and mirror sites, BMRB endeavors to involve the participation of a wider group of scientists and to enhance its services worldwide.