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October 2011 – Page 2

Evaluation of hair growth promoting activity of Musa paradisiaca unripe fruit extract

Anil Sidram Savali, Somnath Devidas Bhinge, Hariprasanna R Chitapurkar

Journal of Natural Pharmaceuticals 2011 2(3):120-124

For the evaluation of the hair growth promoting activity of Musa paradisiaca unripe fruit extract, the study was aimed to investigate the hair growth promoting activity of M. paradisiaca unripe fruit extract. Objective: We examined the effect of M. paradisiaca unripe fruit extract for the hair growth promoting activity, which has been traditionally used for treating hair loss. Materials and Methods: The mice were divided into four groups the extract and minoxidil were applied over the shaved skin surface on to the backs of mice and monitored for 30 days. Results: The extract of M. paradisiaca unripe fruit when tested for the hair growth activity was assed by studying hair length and microscopic study of follicles in vehicle control, 2% minoxidil treated and extract treated animals. Conclusion: The findings suggest that extract of M. paradisiaca unripe fruit has potential as a hair growth promoter.

Evaluation of the effect of the ethanolic extract of Delonix elata on acute inflammation in rats

K Manimekalai, Kartik J Salwe, Harsha M Shetty

Journal of Natural Pharmaceuticals 2011 2(3):149-153

Background: The ethanolic extract of Delonix elata was studied for its effect on the acute inflammation and comparison of its ulcerogenic potential with ibuprofen. Materials and Methods: The ethanolic extract of the leaves of D. elata was obtained using the Soxhlet apparatus. Swiss albino mice weighing 20-30 g and Wistar albino rats weighing 120-130 g of either sex were used in the study. The antinociceptive property of the plant extract was screened by acetic acid-induced writhing in mice while the anti-inflammatory property was studied using the carrageenan-induced paw edema in rats. The gastric irritant action was tested by administering the drug orally and screening the gastric mucosa macroscopically and microscopically after acute administration of the D. elata extract in rats. The percent inhibition of the writhing response and paw edema was noted. The stomach were excised and opened along the greater curvature. The severity of ulcers was scored from 0 to 5 depending on the size and severity of ulcer. Results: The plant extract at a dose of 100 and 200 mg/kg showed a significant reduction in writhing with 55.56% and 54.76% of inhibition, respectively, and also showed a significant dose-dependent reduction in the volume of paw edema with approximately 55.78% and 66.31% of inhibition, respectively. The histological section after the acute administration of ibuprofen indicated superficial erosion. In contrast, after acute treatment of D. elata, it was found that the surface epithelium was intact. Conclusion: The present results indicate that D. elata may be considered safer than the conventional nonsteroidal anti-inflammatory drugs (NSAIDs) with respect to gastric irritation potential.

Department of Pharmacognosy and Phytochemistry, KLEU’S College of Pharmacy

Pharmacognosy is study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.

The Department conducts research work such as Phytochemical screening of natural drugs based on Ethnobotanical clues or traditional usage based on folklore. Plant preparations are said to be medicinal or herbal when they are used to promote health beyond basic nutrition. The study of drugs from plants includes the subjects of botany, chemistry and pharmacology. (more…)

Department of Pharmacognosy and Botany, Tbilisi State University

Department of Pharmacognosy and Botany was established in 1919 as the “Cathedra of Pharmacy and Pharmacognosy” at pharmaceutical division of Tbilisi State University. The first chief of the cathedra was Academician I. Kutateladze (1921-1925). From 1926 the Cathedra of Pharmacognosy became an independent unit, which, as the subordinate of Pharmaceutical and Medical Institute, was managed by Prof. E. Aboll (1926-1952), Prof. V. Shotadze (1952-1962) and Prof. L. Eristavi (1962-1997). Since 1997 the cathedra has been headed by Prof. J. Kuchukhidze. From 1930, the course of botany was added to the Cathedra of Pharmacognosy, which, after organization of Pharmaceutical Institute, was rearranged into the Cathedra of Botany, and from 1953 was joined to the Cathedra of Pharmacognosy as an independent docent course. (more…)

Department of Pharmacognosy, Yerevan State Medical University

Education

Teaching at the department is conducted for the 2nd and 3rd year students of the faculty of Pharmacy on the following subjects: Pharmaceutical Botany (for the 2nd year students) and the main program of Pharmacognosy (for the 3rd year students). At the end of the educational program students undergo summer practical courses and take final exams by the unified testing form. MA course includes the following subjects: “The standardization, certification and quality control of crude drugs of plant and “Pharmacognosy based on the principles of Phуtotherapy”. (more…)

Department of Pharmacognosy, Kwame Nkrumah University of Science and Technology

Pharmacognosy, defined as the study of the physical, chemical, biochemical and biological properties of drugs or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources is a specialized area of applied science which deals with natural products that affect the health of humans and animals. Due to the widespread use of botanicals in developing as well as their resurgence in industrialized nations, significant concerns have been raised about their quality, safety and efficacy. Pharmacognosy plays a critical role in ensuring the authenticity, purity and consistency of the materials employed in this regard. It contributes significantly to the practice of Pharmacy and Herbal Medicine. The Department of Pharmacognosy offers various courses as part of the 4 year Bachelor of Pharmacy (B.Pharm) and Bachelor of Science in Herbal Medicine (BSc. Herbal Medicine) degree programmes. (more…)

Division of Medicinal Chemistry & Pharmacognosy, The Ohio State University

The areas of medicinal chemistry and pharmacognosy focus on the interdisciplinary application of chemical and biochemical principles to the identification and development of therapeutic agents. Research in medicinal chemistry includes the synthesis of organic medicinal products, elucidation of the biochemistry of medicinal agents, examination of the relationship of chemical structure to biological activity, qualitative and quantitative analysis of drugs and related products, and application of computational chemistry to drug design. Research in pharmacognosy encompasses the isolation and structure determination of pharmacologically active natural products from plants and microbes, studies on the structure and biochemistry of biological products, examination of the biosynthesis of natural products, and evaluation of the biochemical effects of these active constituents. (more…)

Department of Pharmacognosy and Pharmaceutical Botany, Prince of Songkla University

The Faculty of Pharmaceutical Sciences, Prince of Songkla University, is the first institution of higher learning in Pharmaceutical Sciences in southern Thailand which offers study programs in undergraduate level and higher. It was initially set up as a unit in the Establishment of Medical Sciences Center Project, Prince of Songkla University, in 1972. The Faculty was formally established in 1978, with assistant professor Dr. Sunalinee Nikrothanonta as the first Dean. The first batch of students was admitted, through the direct entrance examination, into the Bachelor of Pharmaceutical Sciences program, in 1979. Up to the academic year 2008, a total of 30 batches of students have been admitted and the Faculty has produced more than 2,000 graduates to serve the country.

URL : http://www.pharmacy.psu.ac.th/

Department of Pharmacognosy- Institute of Pharmaceutical Sciences

Pharmacognosy

Starting from microscopy, pharmacognosy has developed into a hightech science during the last 40 years. Today, it plays an integral role in the field of Pharmaceutical Sciences through the discovery, identification, and evolution of bioactive compounds from natural sources. Studies of plants used in European, North American, African, and Asian traditional medicine are conducted with the goals of identifying bioactive constituents and discovering new lead compounds.

Pharmaceutical Screening

Main interests are in the field of plant constituents with anti-inflammatory, immunomodulatory, antioxidant, as well as antimicrobial activities, with a spezial emphasis on antimycobacterial activity. The inhibition of leukotriene biosynthesis in human granulocytes by 5-LOX and inhibition of 12(S)-HETE formation by 12-LOX in human platelets as cellular tests, and inhibition of prostaglandin biosynthesis by COX-1 and COX-2 as enzymatic in vitro assays, are established in our Department for screening and testing of extracts and pure compounds with anti-inflammatory activity. (more…)

Department of Pharmacognosy, Wroclaw Medical University

The Faculty of Pharmacy was established in 1946 as part of the Pharmacy Unit at the Faculty of Medicine of the Wroclaw University and Technical University, and in 1950 it became the Faculty of Pharmacy at Wroclaw Medical University. In the 1957/1958 academic year, five-year courses were introduced which ended with the graduates writing and defending their master’s theses. In the 1979/1980 academic year, the Medical Laboratory Diagnostics Unit was established to educate future medical laboratory workers and clinical pathologists. (more…)

Department of Pharmacognosy, Faculty of Pharmacy, Charles University in Prague

Education Overview

There are six subjects taught at the Department of Pharmacognosy: Pharmacognosy, Biotechnology, Technology of Natural Drugs, Ecology for Pharmacists, Monitoring of the Environment, and Phytotherapy (Phytotherapy is guaranteed together with the Department of Pharmaceutical Botany and Ecology).

Research Overview

Research is focused on the study of therapeuticallysignifi cant substances of natural origin (higher plants) with a special attention to their identifi cation and factors infl uencing their biosynthesis. For these purposes, cultures in vitro derived from relevant intact plants are used. (more…)

The Department of Pharmacognosy and Phytochemistry, Amrita Vishwavidyapeetham University

The Department of Pharmacognosy and Phytochemistry at Amrita Vishwavidyapeetham University is an academic department in the School of Pharmacy. The goal of the department of Pharmacognosy and phytochemistry is not only to excel in the field of education but also to conduct social and charitable outreach programs. The department seeks to bridge the ever- widening gap between modern pharmaceuticals and traditional drug systems. Towards this end our department also has programmes for phytochemists to do research on isolation of molecules of herbal drugs as part of pharmacological studies, with phased clinical trials. AIMS (more…)

The Department of Pharmacognosy and Chemistry of Natural Products of the Faculty of Pharmacy (University of Patras)

The Department of Pharmacognosy and Chemistry of Natural Products of the Faculty of Pharmacy (University of Patras) is a multidisciplinary Laboratory which emphasizes Chemical Science at the interface of Chemistry and Biology. Beyond the teaching duties in the graduate and post-graduate level, the major research focus of the Laboratory is the synthesis, the conformational analysis and the structure-activity studies on bioactive peptides and peptides analogues of therapeutic and/or diagnostic significance. (more…)

Professor Norman Farnsworth Dies at 81

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