All about Pharmacognosy

All about Pharmacognosy

Archive for February, 2011

Natural Products Isolation

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The term “natural products” spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in medicine, agriculture, cosmetics, and food in ancient and modern societies around the world. Therefore, the ability to access natural products, understand their usefulness, and derive applications has been a major driving force in the field of natural product research.

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Written by najib

February 10th, 2011 at 2:29 pm

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Pharmacognosy—A Brief History

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‘Pharmacognosy’—has been coined by the merger of two Greek words Pharmakon (drug) and Gnosis (knowledge) i.e., the knowledge of drugs. The nomenclature—‘Pharmacognosy’ was used first and foremost by C.A. Seydler, a medical student in Halle/Saale, Germany, who emphatically employed Analetica Pharmacognostica as the main title of his thesis in the year 1815. Besides, further investigations have revealed that. Schmidt has made use of the terminology ‘Pharmacognosis’ in the monograph entitled Lehrbuch der Materia Medica (i.e., Lecture Notes on Medical Matter) which dates back to 1811, in Vienna. This compilation exclusively deals with the medicinal plants and their corresponding characteristics.

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Written by najib

February 10th, 2011 at 2:05 pm

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Metabolomics Fiehn Lab

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Biomedical Research

This project is a 5-year collaborative effort between the Fiehn laboratory and environmental health researchers (Kent Pinkerton, CHE at UC Davis and Jesse Joad, UC Davis Medical School) to characterize the development of asthmatic-type respiratory malfunctions in newborn and young adult rats, caused by environmental tobacco smoke (ETS).

Diagnosis and prediction of individual responses of human patients to pharmaceutical drugs (NIH GM078233 and ARRA RC2)

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Written by najib

February 9th, 2011 at 9:31 am

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Arabidopsis Gene Expression Database

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Welcome to Arex, which stores genome-wide (Affymetrix microarray) and gene-specific (in situ, GFP-reporter, etc.) Arabidopsis spatial gene expression data. Currently, Arex only stores data from the root, but we wish to include data from other organs in the future. Use the various types of searches below to search through our database, or use the Database menu on the left to browse.

There is no need to register to browse publicly accessible data. You will need to register first, however, to be able to enter data or view restricted access data, or to be informed of future developments by email.

Please see the About page for more information about the database.

To search the AREX database, please specify what you would like to search for in the drop down menu below and then fill in as many search criteria as you wish.

URL : http://www.arexdb.org

Written by najib

February 9th, 2011 at 9:21 am

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The European Arabidopsis Stock Centre

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The Nottingham Arabidopsis Stock Centre (NASC) provides seed and information resources to the International Arabidopsis Genome Programme and the wider research community.

It was established in April 1991 as part of the Plant Molecular Biology initiative of the Agricultural and Food Research Council (AFRC). It is based in the Plant Science Division of the School of Biosciences at the University of Nottingham, Sutton Bonington Campus, UK. Maps of the campus and directions to get here are available. The Centre is funded by the Biotechnology and Biological Sciences Research Council (BBSRC), the EU and the University of Nottingham.

The Stock Centre is managed by Sean May.

NASC’s activities are coordinated with those of the Arabidopsis Biological Resource Center, (ABRC) based at Ohio State University, USA. This facilitates a unified and efficient service for the research community.

The stock centres have a distribution agreement. NASC distributes to Europe and ABRC distributes to North America. Laboratories in other locations may establish their primary affiliation with either centre.

URL : http://arabidopsis.info/

Written by najib

February 9th, 2011 at 9:13 am

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The Arabidopsis Information Resource

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The Arabidopsis Information Resource (TAIR) maintains a database of genetic and molecular biology data for the model higher plant Arabidopsis thaliana . Data available from TAIR includes the complete genome sequence along with gene structure, gene product information, metabolism, gene expression, DNA and seed stocks, genome maps, genetic and physical markers, publications, and information about the Arabidopsis research community. Gene product function data is updated every two weeks from the latest published research literature and community data submissions. Gene structures are updated 1-2 times per year using computational and manual methods as well as community submissions of new and updated genes. TAIR also provides extensive linkouts from our data pages to other Arabidopsis resources.

The Arabidopsis Biological Resource Center at The Ohio State University collects, reproduces, preserves and distributes seed and DNA resources of Arabidopsis thaliana and related species. Stock information and ordering for the ABRC are fully integrated into TAIR.

URL : http://www.arabidopsis.org/

Written by najib

February 9th, 2011 at 9:07 am

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Ethnopharmacology of Medicinal Plants Asia and the Pacific

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In 1860, Oliver Wendell Holmes pointedly expressed himself to the Massachusetts Medical Society: “I firmly believe that if the whole Material Medica, as now used, could be sunk to the bottom of the sea, it would be all the better for mankind, and all the worst for the fishes.” Should one think the same about the current approach in drug discovery from plants? Probably yes. Despite the spending of billions of US dollars, and three decades of efforts, high-throughput screenings have only allowed the discovery of a couple of drugs.

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Written by najib

February 8th, 2011 at 4:08 am

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A Treatise On Phytochemistry

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Medicinal plants are significant source of synthetic and herbal drugs. Medicinal plants have been used for the treatment of diseases since antiquity. India and China have been on the forefront when we talk about history of herbal drugs. The traditional systems of medicines viz. Ayurveda, Siddha, Unani, Western Herbal Medicine, Traditional Chinese Medicine and Homeopathy have roots in medicinal herbs. Herbal medicine has produced number of distinguished researchers and due to its accessibility to traditions it is still practiced even by lay practitioners.

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Written by najib

February 8th, 2011 at 3:58 am

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Modern Phytomedicine:Turning Medicinal Plants into Drugs

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Medicinal preparations derived from natural sources, especially from plants, have been in widespread use since time immemorial. Ancient texts of India and China contain exhaustive depictions of the use of a variety of plant-derived medications. In fact, plants remain the main source of medicines for a large proportion of the world’s population, particularly in the developing world, despite the advent of the pharmaceutical chemistry during the early twentieth century, which brought with it the ability to synthesize an enormous variety of medicinal drug molecules and allowed the treatment of previously incurable and/or life-threatening diseases.

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Written by najib

February 7th, 2011 at 10:01 am

Medicinal Natural Products A Biosynthetic Approach

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This book has been written primarily for pharmacy undergraduates to provide a modern text to complement lecture courses dealing with pharmacognosy and the use of natural products in medicine. Nevertheless, it should be of value in most other courses where the study of natural products is included, although the examples chosen are predominantly those possessing pharmacological activity.

For centuries, drugs were entirely of natural origin and composed of herbs, animal products, and inorganic materials. Early remedies may have combined these ingredients with witchcraft, mysticism, astrology, or religion, but it is certain that those treatments that were effective were subsequently recorded and documented, leading to the early Herbals. Read the rest of this entry »

Written by najib

February 7th, 2011 at 9:40 am

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